New Research Group to Target Autoimmune Disorders

Endothelial Progenitor Cells: New Targets to Control Autoimmune Disorders

An Introduction to Focus Group Research

A focus group refers to a group of people who share some common characteristics. A researcher gathers these people in the group in order that they share their points of view and interact with each other over a specific issue. Focus group and Interview group are used interchangeably in the scientific literature and both refer to a method of collecting data in qualitative studies. Given the impor...

P 86: CD166 as a Therapeutic Target in Autoimmune Diseases

About 3 decades ago CD6 identified as one of the first antigens expresses on the majority of T cells and a subset of B cells. CD6 regulates cellular adhesion migration across the endothelial and epithelial cells. In recent years researches indicate its role in pathogenesis of autoimmune diseases. Many researches have been done in recent years to block CD6 by CD6 mono clonal antibodies, IOR-T1 a...

The new era of autoimmune disease research

Recent genome-wide association studies have advanced our understanding of genetic factors that underlie systemic lupus erythematosus (SLE), a multifactorial autoimmune disease characterized by various clinical manifestations. SLE also has an environmental component, which can trigger or exacerbate the disease. Despite extensive efforts aimed at elucidating the cellular and biological abnormalit...

New insights into the pathogenesis of cutaneous autoimmune disorders.

T helper 17 (Th17) cells are characterized by the secretion of IL-17, a proinflammatory cytokine. They represent a newly described T helper subpopulation that is distinct from Th1 and Th2 lineages. Because of their pleiotropic activity on fibroblasts, keratinocytes, endothelial cells, neutrophils and memory T cells, Th17 cells are thought to be crucial in mediating tissue inflammation and autoi...